FAQ – Science

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Stem Cells

What kind of stem cells are in your products?

Our products contain molecules from adult human stem cells, that reside in the deep dermal layer and subcutaneous layer of the skin. These are the resident stem cells in the skin that repair and maintain our skin throughout our lifetime.

Where do your stem cell released molecules come from?

NeoGenesis sources the stem cell released molecules from healthy human donors that go to tissue banks within the United States. They are carefully tested and the process is highly regulated by the FDA.

Do you use embryonic stem cells?

No, we do not. Our products contain the molecules released from adult human stem cells.

How do NeoGenesis products differ from competitors using bone marrow or platelet derived stem cells? 

Because the molecules from skin stem cells have been studied for a long time and using long term follow-up studies, NeoGenesis products are safe and effective and no problems have been found. The basis of our technology began in the late 1800s in Germany with skin grafting, fat transfers, and more recently skin stem cell transplantations. All have been found to be safe with long term use in contrast to bone marrow and platelet derived stem cells. We published our own safety study a few years ago: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7421258/

How do plant stem cells compare with adult human stem cells?

Plant stem cells cannot influence the cells in human skin. Plant stem cells are beneficial only in that they can work as other antioxidants do, in the fight against free radicals. They have some value as antioxidants, but that capability will break down easily if not stored correctly. Human stem cells release the molecules that have cell to cell communication with skin cells. They speak the same language and are perfectly suited to repair the skin.

What are the percentages of stem cell released molecules in the NeoGenesis products?

Recovery 70%, Booster 40%, Skin Serum 20%, Eye Serum 10%, Intensive Moisturizer 5%, Light Moisturizer 5%, Moisturizing Mist 1%, Hair Serum 60%, NeoLash 60%, NeoBrow 60%.

In order for stem cells to survive they have to be kept moist. What does NeoGenesis use to achieve this?

Storage of the stem cells is in a moist environment that replicates the body’s natural environment for the cell. The body is mostly water, but with many factors, such as proteins, sugar molecules, fat molecules, and metabolites that maintain cellular function. The water with the many factors is what NeoGenesis uses to store stem cells. For long term storage of the cells, a special cryogenic method is used where the cells are carefully frozen, and then carefully unfrozen for use such that ice shards are not formed that tear apart the delicate membranes of the cells. These methods have been well developed by scientists over the decades such that the methodology is appreciated by many women who undergo in vitro fertilization where the eggs and the sperm have been preserved using cryogenic preservation methods. 

Is there RNA found in your technology?

MicroRNAs (miRNAs), which are short, single stranded non-coding RNAs, are signaling molecules found in small amounts in our exosomes. They have been found to be important in the therapeutic effects of the molecules released from adult stem cells.

If a donor has had COVID, and/or the COVID vaccine, can that impact the Stem Cells that are used in NeoGenesis Products?

The stem cell types used by NeoGenesis are derived from the skin, and therefore not affected by the SARS-CoV-2 virus given the virus does not infect skin stem cells.

Oncology

Are NeoGenesis products Oncology safe?

Most of our products available in the UK are oncology friendly, except Salicylic Acid Gel, Mandelic Acid 8%, Fresh Face Mask and Volcanic Ash Mask. All masks may be used 6 months after completing any cancer treatments, or sooner if approved by your health care professional. We recommend consulting your physician prior to using either Mandelic Acid 8% or Salicylic Acid Gel after any cancer treatments.

NOTE: If purchasing through our US site, the Enzyme Crème Mask may be used 6 months after completing any cancer treatments, or sooner if approved by your health care professional.

Can growth factors cause cancer?

Some isolated growth factors, particularly where one or a few factors are used at high concentrations may increase the probability of cancerous growth.

Some other stem cell companies products use high levels of EGF, a concern because EGF signals cells to divide. Other stem cell companies products use the growth factors from bone marrow stem cells that have also been found to induce cells to divide.

We do not use such technologies at NeoGenesis. Instead, we use a whole collection of proteins from stem cell types in the skin that normalize skin function and prevent the abnormal division of cells.

In studies performed for FDA approval, the patented technology at NeoGenesis causes no genetic mutations and no ontological effects.

I have heard that growth factors might make other cells grow on your skin like cherry angiomas and brown spots. Do NeoGenesis products make these abnormalities grow? 

Our serums do contain some growth factors, but in small amounts and not just one or a couple of growth factors, but a collection of all of the normal growth factors found in skin. We’ve published studies finding no cancer growth or mutation of cells with high doses of our S²RM® technology. Cherry angiomas are benign and often increase as we age. 

Ingredients

Do NeoGenesis products contain antioxidants?

Yes. The antioxidants are within the molecules. The molecules have what is called “antioxidant cascades”. They are part of the correctly folded proteins that make up our exosome technology we refer to when explaining our products. These antioxidants are very balanced and give the skin exactly what it needs. There are 2 forms of Vitamin C in the Moisturizing Mist but no other antioxidants are added to the other NeoGenesis products.

What antioxidants are part of S²RM® and NeoGenesis moisturizers?

Superoxide dismutase, glutathione peroxidase, HO-1, and catalase are part of the antioxidant mix contained in S²RM®. HO-1 in particular, is good for vascular inflammation. In the moisturizers, butyrate, tocopherol, ubiquinone, and orange oil are antioxidants.

What is Sodium Hyaluronate Butyrate?

Sodium Hyaluronate Butyrate was created to both improve the properties of hyaluronic acid as well as add additional important hydrating and soothing benefits. It lasts much longer in the skin so the benefits are provided throughout the day as it resists enzyme degradation in the skin. It gives an elegant feel to the texture of any product it is included in.

Is there prostaglandin in the NeoGenesis hair products?

We don’t use prostaglandins or any other hormones in our products.